Apply to the Inria Chair of Junior Professor in digital health

The Inria Centre at the University of Lille and its partners are creating a junior professorship in digital health, whose scientific project is to endotype Chronic Inflammatory Diseases.

Chronic inflammatory diseases (CID) are characterized by significant clinical heterogeneity which complicates patient management. A key concept in personalized medicine is "endotype" as a disease subtype defined by a molecular mechanism or a particular response to treatment. The "ENDOMIC" team led by Prof. Vincent Sobanski (Lille University and University Hospital of Lille, Junior IUF member) aims at revealing endotypes of CID through an integrative multidimensional analysis of highly phenotyped patients. It is based on their clinical and followup data (low dimensional information) and on multi-omics profiles generated specifically for this project (high dimensional information).

Selected among the five national winners of the AMI "Inserm-Inria Digital Health 2020 project-team", this project constitutes a major advance towards an innovative classification because it integrates a very large number of variables by taking into account the temporal dimension and aims to design sequential validation tools to verify the relevance of such an integrative classification. An important originality of this project is to work on making the endotypes intelligible and exploitable by developing a man-machine interface allowing the actors (researchers, practitioners and even patients) to appropriate this new way of classifying a disease.

The candidate will participate in the teaching related to precision health (Health and Digital Hubs of the ULNE I-SITE in the framework of the Experimental Public Establishment project) by bringing his/her specific expertise (data science, artificial intelligence, unsupervised analysis). This "precision health" graduate program is open to biologists, physicians and pharmacists, as well as to (bio)computer scientists of national and international origin, in order to train the next generation of research leaders for academia, industry and the biotechnology world.

It includes a Master's program in Biology and Health (M2) and a PhD program, open to the entire scientific community. It is structured around interactive seminars on current cutting-edge technologies and approaches (e.g., big data, OMICS, next-generation sequencing, systems biology and integrated bioinformatics, AI, mathematical modeling of biological systems, innovative therapies, cohort management, health economics and ethics). He/she will be able to develop specific teaching or join the teaching team in order to structure and lead this strategic training offer for the University of Lille.